Men's Health Resource Center (MHRC)

OptiMind Vs. Brain Pill: Detailed Review of The Good & The Bad

OptiMind vs. Brain Pill

Nootropics are a hot topic these days, and thousands of men and women are out looking for a quick-fix pill that can uplift their mental well-being and help them get through the day with a sharp and relaxed mind.

When it comes to choosing a nootropic supplement, the choices seem endless and confusing. There are literally thousands of brand and generic brain supplements to choose from, and almost each one of them has both positive and negative reviews; happy and angry customers.

In this article I'm going to review two pre-made natural nootropic stacks that are often top-rated in this category, namely OptiMind and Brain Pill.

What Exactly Is It?

Both OptiMind and Brain Pill are over-the-counter dietary supplements used to improve brain health and mental performance.

OptiMind comes in capsule form and it is made in the US by AlternaScript.

Brain Pill is also a capsule that is manufactured in the US and sold and distributed worldwide by a Canadian-American company called Leading Edge Health.

How Effective Is It?

OptiMind is as good as a cup of coffee. It actually does contain caffeine alongside some other herbal ingredients (list below) for mental support. It can help you stay awake and focused as you mind your daily business.

Brain Pill can help you stay relaxed, focused, refreshed and mentally clear. It is designed for long-term daily use, and it may take a few weeks to realize the full benefits of this herbal blend.

Neither of these pills is a quick-fix brain booster - like Adderall, Ritalin, and other stimulant drugs - but they are good herbal products for moderate brain enhancement. They don't mess up your brain chemicals and natural flow like stimulants do.

How to Take It?

The recommended serving of OptiMind is 2 capsules taken in the morning. According to the label, it's ok to take up to 5 capsules in a day given that you don't take more than 2 within 3-4 hours.

For Brain Pill, the recommendation is also 2 capsules a day; 1 in the morning and another in the afternoon. The maximum allowed daily dose is 4 capsules, as per label instructions.

Normally, you'd want to take these every day but you can also use them as needed. Take the capsule with a glass of water. Food is optional, so try it with and without and see which works better.

Efficacy and results can vary from one individual to another. Not everyone may need the same dosage, so while keeping these instructions in mind, you'll need to figure out the right dosage and timing that work best for you.

What Are The Ingredients?

The following is a list of all the active ingredients in OptiMind as declared on the label (indicated dosage is per 1 serving or 2 capsules):

  • Vitamin D (385 IU)
  • Vitamin B12 (500 mcg)
  • Calcium (44 mg)
  • Magnesium (16 mg)

[Focus Blend:] (1,288 mg total)

  • Bacopa Monnieri (Synapsa)
  • L-Taurine
  • Phosphatidylserine (SerinAid)
  • Gamma-Aminobutyric Acid (GABA)
  • Caffeine
  • L-Tyrosine
  • Alpha Lipoic Acid
  • Vinpocetine
  • Huperzine A
  • Sulbutiamine

And these are the active ingredients in Brain Pill with the specific dosage of each ingredient per serving (2 capsules):

  • Vitamin B6 (5 mg)
  • Folic Acid (Vitamin B9) (400 mcg)
  • Vitamin B12 (50 mcg)
  • Pantothenic Acid (Vitamin B5) (30 mg)
  • Cognizin (250 mg)
  • Synapsa (Bacopa Monniera) (320 mg)
  • L-Tyrosine (175 mg)
  • Phosphatidylserine (100 mg)
  • Ginkgo Biloba Extract (100 mg)
  • DHA Complex (Omega-3 Fish Oil Powder) (100 mg)
  • L-Theanine (100 mg)
  • Huperzia Serrata Extract (1% Huperzine A) (5 mg)
  • Vinpocetine (5 mg)

The Good About OptiMind

Natural and Safe

All of the ingredients in this formula are obtained from natural sources. They have been the subject of many different third-party studies with proven effectiveness and safety.

You can take OptiMind as instructed every day for as long as you'd like without suffering from any significant side effects.

Made in the USA

OptiMind is manufactured in a GMP-certified facility that adheres to FDA regulations. The product however is not approved by the FDA since it's a dietary supplement not a drug.

The Bad About OptiMind

Free Trial Hook

Personally I'm not a fan of free trial products, particularly if it is a supplement. There is always a catch in a "free trial", and the catch here is that once you order the free trial you are automatically enrolled into a monthly subscription, where they will auto-charge your credit card and send you a new shipment every month until you cancel.

Not everyone may pay attention to the details or be able to cancel in time, which will result in an unexpected and unwanted credit card charge (this has happened to some customers). If you want to give me a free trial don't auto-charge me for further shipments unless I ask for it, otherwise it gets a thumbs down from me!

Contains Caffeine

Caffeine works -- we all know that, and most people take their daily dose of caffeine from coffee, tea and/or other caffeinated drinks, while others try to avoid caffeine altogether.

Putting caffeine in a nootropic supplement seems questionable to me. It makes it hard to tell if the other ingredients actually work, or it's just the caffeine effect.

Proprietary Formula

The product label only shows the aggregate dosage of all the main 10 ingredients combined, but it does not specify the exact amount of each ingredient.

The company claims the formula is sort of a trade secret that they don't want to give out to competitors, but that's more of a marketing hype with no scientific basis. All of the ingredients are widely known and used by others, and most manufacturers will tell you exactly how much of each ingredient you're getting -- this includes most top-of-the-line brands.

I normally avoid supplements that do not list the specific amount of each ingredient on the label. I'd like to know exactly what I'm putting into my body, and I also like to do my own research about the effective dosage of each ingredient through third-party websites rather than just taking the manufacturer's word for it.

Another concern I'd have here is that some ingredients may be underdosed. They do list the total dosage of the Focus Blend in the formula, and that is 1,288 mg (1.288 g) for 10 ingredients combined, but is that an adequate dosage? Let's just take one of those 10 ingredients; Gamma-Aminobutyric Acid (GABA). In clinical studies where GABA was used, the tested dosage ranged from 800 mg up to 5,000 mg!


One bottle of OptiMind costs $43.31 and contains 16 servings (32 capsules). That's not a cheap supplement, but then most brand supplements are rather marked up.

The Good About Brain Pill

Natural Nootropic

Brain Pill contains 13 natural ingredients including herbal extracts, vitamins, and amino acids. This pill packs a variety of brain-enhancing nutrients that anyone looking for natural nootropics should try.

Made in the USA

This supplement is produced in the US by a cGMP-compliant facility.

The Bad About Brain Pill

Tall Claims

The manufacturer promises a long list of benefits that it almost sounds too good to be true. Truth is, while this supplement can help a little, the results are not as impressive as advertised.

It is not going to give you any extraordinary mental advantage or make you smarter than others. It is simply just a nutritional support for brain health and performance.

A Starter Dose

Some of the ingredients in Brain Pill come at an average dosage while others are at the minimum effective dosage. This may work well for a beginner, but if you are an old-time herbal nootropic user you may need to double the dose to get noticeable results.


Brain Pill is also on the pricey side. One box costs $79.99 and packs 30 servings (60 capsules).

Any Side Effects or Safety Issues?

There are no significant side effects associated with either of these two supplements.

You should be careful when taking OptiMind with coffee or any other drink that contains caffeine, since this supplement already contains caffeine. Too much caffeine can cause jitters, anxiety, headache and other negative side effects.

There is no information about drug interactions, but if you take other drugs or supplements for a specific health condition it is always advised to talk to your doctor first.

Final Thoughts and Recommendation

Both OptiMind and Brain Pill offer a good formula of herbal nootropics, and are worth considering for any adult in search of an all-in-one OTC brain enhancer. Each product has its strengths and weaknesses, and you may want to give each a try. But if I had to make a choice between the two I'd go with Brain Pill for these reasons:

  • The label shows exactly the amount of each ingredient you get per serving.
  • Contains four B-vitamins (B5, B6, B9, B12), which have been shown to slow memory decline and help with brain fog.
  • Contains Ginkgo Biloba, which is a highly popular and recommended herb that may improve circulation and cognitive function.
  • Contains L-Theanine, which reduces stress and improves sleep quality.
  • Does not contain caffeine.
  • No auto-shipments.

Where to Buy?

These two products are only sold online. OptiMind only ship to the United States while Brain Pill can deliver to most countries. Here are the links to the official websites where you can find more information and order online.

Official OptiMind website

Official Brain Pill website